A 26-8 blitz from the hosts in the second half brushed aside the challenge of Peter Buckleâ€
s side, who were led by a game-16 points from Temi Fagbenle.
GB could not resist the all-consuming pressure from the Lithuanians who forced 23 turnovers and a succession of bad shots, while also profiting from their efficient outside shooting.
And with a 2-1 record, the British now travel onwards to Antwerp for what could be a pivotal game with Belgium on Wednesday night.
Fagbenle scored eight in the opening period as the visitors claimed a 13-11 after ten minutes but their hopes of an upset slipped rapidly away.
A 9-0 run put Lithuania in control as they eased into a 35-20 lead at half-time.
With Stef Collins – who ended with 14 points and ten rebounds – in foul trouble, Buckleâ€
s women were held scoreless for over four minutes as their Group B rivals reeled off eleven points without reply.
And Lithuania, paced by 14 points and six rebounds from their canny centre Gintare Petronyte, used 6/14 shooting from three-point range to cruise as much as 72-48 clear as they coasted to their third win of this campaign to edge to the brink of qualification for next yearâ€
s finals in Hungary and Romania.
Gabriele Gutkauskaite and Kamile Nacickaite also scored 14 apiece for the victors.
Elsewhere, the Belgians picked up their opening win with a comprehensive 94-66 defeat of Macedonia.
Group B standings:
1. Lithuania (3-0)
2. Great Britain (2-1)
3. Belgium (1-2)
4. Macedonia (0-3)
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